@ARTICLE{10.21494/ISTE.OP.2020.0530, 

TITLE={What can mathematical modelling contribute to the mastery of bio-printing?}, 
  
AUTHOR={Danzo A., André J.C, }, 
	
JOURNAL={Entropy: Thermodynamics – Energy – Environment – Economy }, 
	
VOLUME={1}, 

NUMBER={Issue 2}, 
	
YEAR={2020}, 

URL={https://openscience.fr/What-can-mathematical-modelling-contribute-to-the-mastery-of-bio-printing}, 
	
DOI={10.21494/ISTE.OP.2020.0530}, 
	
ISSN={2634-1476}, 
	
ABSTRACT={Bio-printing from additive manufacturing technologies is developing in terms of scientific research because with this recent technology it would be possible, with stem cells from people with serious diseases, to one day recreate deficient organs without rejection from sick patients since these organs would be recreated from compatible healthy cells. What is observed is an almost exponential increase in the volume of experimental publications, while the modelling of cell growth and differentiation processes remains little explored. Nevertheless, bio-printing requires the convergence of many scientific disciplines, which imposes an epistemological reflection aimed at robust organ production. In the absence of the possibility of a deep association between the scientific specialists concerned, mathematical modelling makes it possible to attempt to find possible paths existing between the extraction of healthy cells from a patient and the potential production of a tissue, or even an organ. The aim of this work is to illustrate this potentiality, making it possible to know what questions to ask biologists in order to make progress on this subject (in particular), but also to know the limits of this type of exercise.}}